Senior Principal Biostatistician

Role summary

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The Senior Principal Biostatistician leads statistical strategy for clinical development and regulatory submissions, designing studies, developing analysis plans, interpreting results, and communicating evidence to multidisciplinary teams. Requirements typically include an advanced degree in biostatistics, statistics, or a related discipline; substantial experience in clinical trials and pharmaceutical research; strong knowledge of statistical methodology, SAS or R, and regulatory standards such as ICH; and experience guiding junior statisticians. Novartis expects an influential, scientifically rigorous candidate who can work across functions, manage complex projects, explain statistical concepts clearly, and contribute to innovative approaches in drug development. Strong collaboration, problem-solving, and written and verbal communication skills are essential.

About the employer

Novartis is a global pharmaceutical company headquartered in Basel, Switzerland, focused on discovering and developing innovative medicines. Its research and commercial activities span areas including cardiovascular, renal and metabolic diseases, immunology, neuroscience, oncology, and rare diseases. The company uses biomedical science, data, technology, and large-scale clinical development programmes to address significant unmet medical needs. Novartis employs people across many countries and brings together scientists, clinicians, statisticians, engineers, commercial specialists, and corporate professionals. In the United Kingdom, it operates across research, clinical development, medical affairs, market access, commercial, and corporate functions. The organisation promotes innovation, evidence-based decision-making, patient impact, inclusion, and collaboration across international teams.

Working in United Kingdom

The United Kingdom offers strong opportunities in pharmaceuticals, biotechnology, healthcare, finance, technology, engineering, and professional services, with major employment centres in London, Cambridge, Oxford, Manchester, Edinburgh, and other regional cities. Its culture is diverse and generally values professionalism, punctuality, privacy, and work-life balance, while social life ranges from historic towns and museums to music, sport, countryside, and coastal activities. Living costs are highest in London and parts of southeast England; public transport is extensive, and the National Health Service provides healthcare for eligible residents. Visa requirements depend on nationality and role. Many skilled professionals use the Skilled Worker visa, requiring an approved sponsor, an eligible occupation, and salary compliance. Candidates should confirm sponsorship, immigration, tax, housing, and relocation support directly with Novartis and the UK government.