This role supports antibody–drug conjugate (ADC) medicinal chemistry research at Astellas in Japan. Candidates are typically expected to hold a degree in medicinal chemistry, organic chemistry, pharmaceutical sciences, or a related discipline, with practical experience in organic synthesis, compound design, purification, characterization, and analytical techniques. Experience with ADC payloads, linkers, bioconjugation, or oncology research is advantageous. The successful candidate should be capable of planning experiments, interpreting scientific data, preparing clear reports, contributing to intellectual property and publications, and working effectively with multidisciplinary teams. Strong communication skills, scientific curiosity, attention to detail, and the ability to manage priorities in a collaborative drug-discovery environment are expected.
Astellas Pharma Inc. is a Japan-based global pharmaceutical company headquartered in Tokyo. It focuses on discovering, developing, and commercializing innovative medicines in areas of significant unmet medical need. Its research interests include oncology, immunology, neuroscience, genetic regulation, and other specialized therapeutic fields. Astellas operates research, development, manufacturing, and commercial organizations across Japan, North America, Europe, and other international markets. The company combines scientific research with partnerships, external innovation, and advanced technologies to create new treatment options for patients. Its employees commonly work in multidisciplinary and international teams, covering early discovery through clinical development and commercialization. Astellas places emphasis on patient-focused innovation, scientific quality, compliance, and responsible business practices.
Japan offers strong opportunities in pharmaceuticals, biotechnology, healthcare, engineering, information technology, finance, education, and advanced manufacturing. Major employment centers include Tokyo, Osaka, Yokohama, Nagoya, and Tsukuba. Workplace culture generally values punctuality, preparation, teamwork, respect for hierarchy, and thoughtful communication, although international companies may have more flexible practices. Lifestyle ranges from highly urban living to quieter regional communities, with excellent public transport, healthcare, safety, and food, but housing and commuting can be costly in Tokyo. Foreign professionals usually need an employer-sponsored work visa, commonly the Engineer/Specialist in Humanities/International Services or a highly skilled professional status, depending on the position. A passport, employment contract, educational records, and supporting company documents are normally required. Applicants should arrange housing, registration, health insurance, tax procedures, and a residence card after arrival.
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