This role leads upstream bioprocess science for drug-substance development within Astellas’s Product Research & Development organization. Candidates are typically expected to hold an advanced degree in biotechnology, biochemistry, chemical engineering, pharmaceutical sciences, or a related discipline, with substantial experience in mammalian or microbial cell culture, bioreactor development, process characterization, and scale-up. The position requires strong knowledge of development principles, data analysis, technical documentation, and collaboration with analytical, formulation, manufacturing, and regulatory teams. A successful candidate will provide scientific leadership, solve complex process challenges, communicate clearly with internal and external partners, and help deliver robust, scalable processes supporting clinical and commercial programs.
Astellas Pharma Inc. is a Japan-based global pharmaceutical company headquartered in Tokyo, with research, development, manufacturing, and commercial operations across multiple regions. The company focuses on innovative medicines in areas such as oncology, immunology, neuroscience, ophthalmology, and urology. Astellas invests substantially in research and development, including biologics, advanced modalities, regenerative medicine, and other emerging technologies. Its Product Research & Development organization works to translate scientific discoveries into medicines for patients with significant unmet medical needs. The company employs international, multidisciplinary teams and collaborates with academic institutions, biotechnology companies, healthcare professionals, and other industry partners. In Japan, Astellas offers opportunities in laboratory science, bioprocessing, clinical development, manufacturing, regulatory affairs, corporate functions, and commercial operations. Benefits and working arrangements vary by position and employment contract.
Japan offers strong opportunities for scientists, engineers, pharmaceutical professionals, software specialists, healthcare workers, and experienced business professionals. Tokyo, Osaka, Yokohama, Tsukuba, and Kobe are major centers for research, manufacturing, technology, and international business. Japanese workplaces value punctuality, preparation, teamwork, respect, and attention to detail, while multinational companies often use English in technical roles. Lifestyle options range from busy metropolitan living to quieter regional communities, with reliable public transport, excellent services, and generally high safety standards. Living costs are highest in Tokyo; housing, commuting, and language support should be considered when relocating. Foreign employees usually need an appropriate work visa, commonly an Engineer/Specialist in Humanities/International Services visa or a Highly Skilled Professional visa. Employers often support sponsorship, but requirements include a valid offer, qualifications, and documentation. Learning basic Japanese can significantly improve daily life and workplace integration.
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