The Process Engineer II (Upstream) supports upstream biopharmaceutical manufacturing at Takeda’s Singapore operations. Responsibilities typically include operating and improving cell-culture and fermentation processes, troubleshooting production issues, preparing technical documentation, supporting investigations and CAPA, and maintaining compliance with GMP, safety, and quality standards. Candidates are expected to hold a degree in biochemical, chemical, biological, or related engineering, with relevant experience in upstream processing, biotechnology manufacturing, or process development. Knowledge of bioreactors, aseptic processing, process validation, data analysis, and regulated production environments is valuable. The role requires strong problem-solving, communication, teamwork, documentation, and shift or manufacturing-site flexibility.
Takeda Pharmaceutical Company is a global, research-driven biopharmaceutical company headquartered in Japan, with operations across North America, Europe, Asia, and other markets. It develops and supplies medicines in areas including gastroenterology, rare diseases, plasma-derived therapies, oncology, neuroscience, and vaccines. Takeda combines research, advanced manufacturing, and partnerships to address significant healthcare needs. Its Singapore operations support regional and global biopharmaceutical production and supply, including sophisticated manufacturing and quality activities. The company promotes a values-based culture centered on patient focus, integrity, fairness, honesty, and perseverance. Employees commonly work in multidisciplinary, international teams and are expected to follow rigorous standards for safety, quality, compliance, and continuous improvement.
Singapore is a compact, highly connected island city-state and a major Asian hub for pharmaceuticals, biotechnology, engineering, finance, and technology. Opportunities are strong for professionals with GMP manufacturing, bioprocessing, quality, engineering, supply-chain, and data skills, particularly in multinational companies and research institutes. The culture is multicultural, efficient, and generally workplace-oriented, with English widely used professionally. Public transport is excellent, healthcare is high quality, and neighborhoods offer diverse food, housing, and recreation, although living costs—especially rent—can be high. Employment visas are normally sponsored by the hiring company; the Employment Pass is common for professional roles and depends on salary, qualifications, and eligibility criteria. Candidates should secure an offer before relocating, check pass requirements, budget carefully for accommodation, and understand tax, insurance, and dependent-pass arrangements.
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